Shiva (Karthikeya) is an angry youngster from Athreyapuram who loses his parents in his childhood. He has been raised by Daddy (Ramki) who is a close friend of Vishawanatham (Rao Ramesh), a politician and businessman. Shiva falls in love with Vishwanatham’s daughter Indhu (Payal) and she soon gets married to an NRI in a surprising move. The rest of RX 100 is all about the struggle Shiva faces after Indhu’s marriage and what happens next. Watch RX 100 to know about the complete story.